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2015). These scientific tests, taken together, counsel that, although a direct activation of GPR55 or PPAR‐α occurs, PEA can create its anti‐inflammatory action during the intestine also by using oblique activation of CB1 and CB2 receptors, in all probability as a result of the power of the compound to potentiate the action of endocannabinoids
Key phrases: fibromyalgia; palmitoylethanolamide; melatonin; nutraceuticals; soreness; snooze; quality of lifePalmitoylethanolamide (PEA) has become prompt to possess handy analgesic Attributes and also to be devoid of undesired consequences. Listed here, We've examined critically this contention, and talked about readily available knowledge in reg